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Title: Hallucinating Brains With Artificial Brains
No: 11377 Writer: 박영훈 :28 2018-07-26
Human brain function as measured by functional magnetic resonance imaging (fMRI), exhibits a rich diversity. In response, understanding the individual vari-ability of brain function and its association with behavior has become one of the major concerns in modern cognitive neuroscience. Our work is motivated by the view that generative models provide a useful tool for understanding this variabil-ity. To this end, this manuscript presents two novel generative models trained on real neuroimaging data which synthesize task-dependent functional brain im-ages. Brain images are high dimensional tensors which exhibit structured spatial correlations. Thus, both models are 3D conditional Generative Adversarial net-works (GANs) which apply Convolutional Neural Networks (CNNs) to learn an abstraction of brain image representations. Our results show that the generated brain images are diverse, yet task dependent. In addition to qualitative evaluation, we utilize the generated synthetic brain volumes as additional training data to im-prove downstream fMRI classifiers (also known as decoding, or brain reading). Our approach achieves significant improvements for a variety of datasets, classifi-cation tasks and evaluation scores. Our classification results provide a quantitative evaluation of the quality of the generated images, and also serve as an additional contribution of this manuscript.